Simmons (ankle) contributed 17 points (5-11 FG, 2-5 3Pt, 5-5 FT), four rebounds and two assists over 34 minutes during Saturday's 74-64 victory over Lindenwood.
Simmons injured his ankle last Saturday against Morehead State and will not be available to play Thursday versus Tennessee Tech, Treasure Washington of The Courier & Press reports.
Lakes (shoulder) logged 17 points (6-7 FG, 4-5 3Pt, 1-2 FT), five rebounds, two assists and one block across 26 minutes during Southern Indiana's exhibition win Wednesday versus Midway.