Yates (ankle) was activated off the 10-day disabled list Thursday, Bob Scanlan of FOX Sports San Diego reports.

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Confirming speculation, San Diego Padres starter Luis Perdomo was optioned Thursday to Triple-A El Paso. Right-handed reliever Kirby Yates (ankle) will be activated from the disabled list Friday. Perdomo had struggled mightily in four starts to a 8.36 ERA and 2.50 WHIP. The Padres haven't announced Perdomo's replacement, but might stick with starter/reliever Robbie Erlin and are considered promoting prospect Eric Lauer. Meanwhile, Yates was sporting a shiny 0.00 ERA and 0.55 WHIP with five strikeouts through 3 2/3 innings before his injury. He should slot back into his role as the Padres primary setup man. With a career 11.7 K/9 and likely the next man up as closer, Yates could merit deep league consideration for ratios, strikeouts and potential rogue wins and saves.

Yates (ankle) threw batting practice Wednesday, Jeff Sanders of The San Diego Union-Tribune reports.

Yates (ankle) was throwing on the field Thursday, Jeff Sanders of The San Diego Union-Tribune reports.

Yates was placed on the 10-day disabled list Monday.

Padres manager Andy Green said Yates is dealing with right ankle tendinitis and will be evaluated Monday, Kevin Acee of The San Diego Union-Tribune reports.

Yates was removed from Saturday's game due to right ankle inflammation.

Yates was removed from Saturday's game due to an apparent injury, AJ Cassavell of MLB.com reports.

Yates tossed a 1-2-3 eighth inning and collected a strikeout in Tuesday's 8-4 win over the Rockies.

Yates was able to return from his minor ankle injury Feb. 28, pitching a scoreless inning in his spring training debut.

Yates is dealing with a twisted ankle, which the Padres view as a short-term issue, Jeff Sanders of The San Diego Union-Tribune reports.

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San Diego Padres relief pitcher Kirby Yates (ankle) is dealing with a twisted ankle, but the injury isn't believed to be a long-term one. Yates was extremely effective for the Friars in 2017, posting a 3.97 ERA, 1.11 WHIP and 88 strikeouts in 56 2/3 frames. He misses plenty of bats, but the home run ball is his weakness, although it's mitigated pitching home games at Petco Park. If closer Brad Hand is traded in 2018, it's not inconceivable that Yates would be handed the ninth-inning job. He's a handcuff for Hand owners in deeper leagues.

Yates agreed to a one-year deal with the Padres on Friday, avoiding arbitration.

Yates struck out two batters over a scoreless inning Thursday, picking up his 17th hold in a 3-0 win over the Cardinals.

Yates (3-5) blew the lead in Friday's 8-6 loss to the Marlins, giving up three runs on two hits while striking out two.

Yates was reinstated from the family leave list Monday.

Yates was put on the family leave list, Jeff Sanders of The San Diego Union-Tribune reports.

Yates picked up his 10th hold after firing a scoreless inning in Tuesday's 3-0 win over the Phillies.

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San Diego reliever Kirby Yates picked up his first save on Saturday night since Brad Hand was unavailable after three straight days of appearances with a save. Yates could be in line for more save chances the rest of the way if Hand is traded before Monday evening. Yates has suddenly emerged as a shutdown bullpen option, striking out almost 14 batters per nine innings. He holds a 1.78 ERA and 0.96 WHIP on the season. Rookie Phil Maton has also looked good in limited time since his call-up, with a 2.95 ERA, 0.84 WHIP, 10.1 K/9 over 21 1/3 innings. Both are worth a speculative add in deeper leagues if Hand is moved out of town.

Yates fired a clean ninth inning while striking out two Saturday, picking up his first save in a 4-2 win over Pittsburgh.

Yates (personal) was reinstated from the paternity list Monday.

Yates was placed on paternity leave prior to Friday's game.

Yates fired a pair of scoreless innings in relief Sunday, striking out three in a loss to the Rockies.

Yates (1-0) pitched 1.2 scoreless innings without allowing a baserunner and struck out two batters during Sunday's win over Washington.

Yates tossed a scoreless inning and picked up his second hold in Sunday's loss to the White Sox.

Yates was claimed off waivers by the Padres on Wednesday.

The Angels designated Yates for assignment Sunday.

Yates was recalled from Triple-A Salt Lake on Saturday, Jeff Fletcher of the Orange County Register reports.

Yates was outrighted to Triple-A Salt Lake on Wednesday.

Yates' new split-finger fastball may be the secret behind his Cactus League success, the Orange County Register reports.

Yates threw a clean inning in his Cactus League debut Saturday. He will compete for a bullpen job this spring.

Yates was claimed off waivers by the Angels on Wednesday.

Yates was recalled from Rookie-level Pulaski on Friday.

Yates was optioned to Rookie-level Pulaski on Tuesday.

Yates was recalled from Triple-A Scranton/Wilkes-Barre on Wednesday.

Yates was optioned to Triple-A Scranton/Wilkes-Barre on Tuesday.

Yates is carrying a 3.52 ERA with 11 strikeouts in 7.2 innings this season.

Yates will be on the Yankees' Opening Day roster, Wallace Matthews of ESPN New York reports.

Yates remains in the mix for a spot in the Opening Day bullpen, the New York Post reports.

Yates was traded from the Indians to the Yankees on Friday for cash considerations.

Yates was designated for assignment Tuesday, Paul Hoynes of Cleveland.com reports.

Yates was acquired from the Rays in exchange for cash considerations Wednesday, Jordan Bastian of MLB.com reports.

Yates was designated for assignment on Friday, the Tampa Bay Times' Marc Topkin reports.

Yates will be called up when rosters expand Tuesday, Marc Topkin of the Tampa Bay Times reports.

Yates was optioned to Triple-A Durham on Saturday, Bill Chastain of MLB.com reports.

Yates is in danger of being sent down to make roster room for Drew Smyly, Marc Topkin of the Tampa Bay Times reports.

Yates was recalled from Triple-A Durham on Friday, Bill Chastain of MLB.com reports.

Yates was optioned to Triple-A Durham on Tuesday.

Yates was recalled from Triple-A Durham on Tuesday.

Yates (chest) was activated off the disabled list and optioned to Triple-A Durham on Wednesday, Marc Topkin of the Tampa Bay Times reports.